Research Articles
Nature's Traffic Cop: How a Single Enzyme Directs Our Hormones and Health
Exploring the structural basis for CYP17A1's compromised lyase activity with 17-hydroxyprogesterone and its implications for human health and disease.
The Enzyme With a Switch: How Phosphorylation Controls UGT2B7's Substrate Selection
Discover how tyrosine kinase phosphorylation dynamically controls UGT2B7 enzyme substrate selection in cellular detoxification processes.
The Case of the Inactive Enzyme: When a Scientific "Fact" Turns Out To Be Wrong
Discover how recent research revealed that DDAH-2 enzyme doesn't metabolize methylarginines, challenging decades of scientific understanding about cardiovascular regulation.
The ChaC2 Enzyme: How a Cellular Housekeeper Influences Health and Disease
Explore the structural and functional analyses of human ChaC2 enzyme in glutathione metabolism and its implications for cancer treatment and cellular health.